There are evidences for curing other spirochetal infections such as Leptospirosis through treatment using herbs like Sambiloto. Extract of this herb, in the form of an injection or tablets of the crude extract or of the isolated lactones, was reported to effectively treat leptospirosis. In one evaluation, 31 of 35 cases were said to be cured by the Andrographis lactones. There are people who had used Sambiloto treating the Lyme disease (Sambiloto is the best all around herb for Lyme!).